Consensus statement on the safety profile of topical calcineurin inhibitors.
نویسندگان
چکیده
a University of Bonn, Bonn , Germany; b University of Sheffi eld Medical School & Sheffi eld Children’s Hospital, Sheffi eld , UK; c University of Michigan Medical School, Ann Arbor, Mich. , USA; d University of Verona, Verona , Italy; e St. Johns Institute of Dermatology, St. Thomas’ Hospital, London , UK; f Dalhousie University, Halifax , Canada; g University of Münster, Münster , and h Dresden University of Technology, Dresden , Germany; i St George Hospital, University of New South Wales, Sydney , Australia; j NYU School of Medicine, New York, N.Y. , and k Northwestern University’s Feinberg School of Medicine, Chicago, Ill. , USA; l Hôpital Necker-Enfants Malades, Paris , France; m Hospital Santa Creu i Sant Pau, Barcelona , Spain; n Technical University Munich, Munich , Germany; o University Hospital, Geneva , Switzerland; p University of Kiel, Kiel , Germany; q University of Toronto, Toronto , Canada; r Medical University of Vienna, Vienna , Austria; s Central Hospital, University of Bordeaux, Bordeaux , France; t Aarhus University Hospital, Aarhus , Denmark
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Atopic eczema is a chronic inflammatory skin disorder with a relapsing and remitting course. For many decades,topical corticosteroids have been the mainstay therapy for atopic dermatitis. After the introduction of calcineurin inhibitors as a corticosteroid-free alternative, there were high expectations. After the black box warning from the FDA regarding the potential theoretical risk for develo...
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As no cure exists for atopic dermatitis, the goals of treatment include reducing symptoms and prolonging periods between flares. Proper skin care can improve skin barrier function, reducing susceptibility to triggers of flares. Topical corticosteroids and topical calcineurin inhibitors may improve symptoms.
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عنوان ژورنال:
- Dermatology
دوره 211 2 شماره
صفحات -
تاریخ انتشار 2005